I was doing a little light reading today on Mac's condition and found this, a formula to figure out how much of his hormones he should receive depending on the situation. It changes from daily, to "stress dose" which also has 2 categories of "illness" or "trauma". I'm not sure who manages to use these formulas and not go cross-eyed but I thought it would give a little insight into how tough it can be to regulate Mackinley's hormones.
Hydrocortisone:
Replacement doses if needed: 8–15 mg/m2/day PO, divided q8h (or t.i.d.)
In stress circumstances such as fever or illness, dose increased to 25–100 mg/m2/day PO
For surgery, major illness, vomiting: Loading dose of 50–100 mg/m2 IM or IV followed by 50–100 mg/m2 divided q4h; oral stress doses should be divided q8h.
To calculate hydrocortisone dose, estimate body surface area (BSA) using a nomogram or the following formula: BSA (m2) = square root of (height [cm] × weight [kg]/3600)
It made me laugh a little to think about his specialists calculating this.
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